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Genetic analysis of the gene coding for DARPP-32 (PPP1R1B) in Japanese patients with schizophrenia or bipolar disorder

✍ Scribed by Akira Yoshimi; Nagahide Takahashi; Shinichi Saito; Yoshihito Ito; Branko Aleksic; Hinako Usui; Yukiko Kawamura; Yukari Waki; Takeo Yoshikawa; Tadafumi Kato; Nakao Iwata; Toshiya Inada; Yukihiro Noda; Norio Ozaki

Book ID: 119363316
Publisher: Elsevier Science
Year: 2008
Tongue: English
Weight: 201 KB
Volume: 100
Category: Article
ISSN: 0920-9964
DOI: 10.1016/j.schres.2007.10.028

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## ~ A new class of disease (including Hunting ton disease, Kennedy disease, and spinocerebellar ataxias types 1 and 3) results from abnormal expansions of CAG trinucleotides in the coding regions of genes. In all of these diseases the CAG repeats are thought to be translated into polyglutamine tr