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Genetic analysis of Nurr1 haplotypes in Parkinson's disease

✍ Scribed by Eng-King Tan; Henry Chung; Yi Zhao; Hui Shen; V.R Chandran; Chris Tan; Mei-lin Teoh; Yuan Yih; Ratnagopal Pavanni; Meng-Cheong Wong

Book ID
117473980
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
176 KB
Volume
347
Category
Article
ISSN
0304-3940

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Nurr1 mutational screen in Parkinson's d
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✍ Eng-King Tan; Henry Chung; Vandana R. Chandran; Chris Tan; Hui Shen; Kenneth Yew πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 English βš– 59 KB

## Abstract We performed sequence analysis of all the exons and exon–intron boundaries in familial and young‐onset Parkinson's disease (PD) in an Asian cohort. None of the patients carried any pathogenic mutations in the Nurr1 gene. We demonstrated a 5 to 10% prevalence of the intron 7 +33 Cβ†’T vari