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Genetic analysis of NOD2 in patients with intestinal tuberculosis and Crohn's disease in Korea

✍ Scribed by Yosep Chong; Mi Jung Lee; So Young Jung; Joon Mee Kim; Mee-Yon Cho


Book ID
118078416
Publisher
Wiley (Blackwell Publishing)
Year
2009
Tongue
English
Weight
373 KB
Volume
2
Category
Article
ISSN
1755-9294

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Background: NOD2 is an intracellular protein involved in host recognition of specific bacterial molecules and is genetically associated with several inflammatory diseases, including Crohn's disease (CD). NOD2 stimulation activates the transcription factor, NF-B, through RIP2, a caspase-recruitment d