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Non-association of Crohn's disease with NOD2 gene variants in Moroccan patients

✍ Scribed by I. Hama; I. Ratbi; S. Reggoug; F. Elkerch; G. Kharrasse; I. Errabih; H. Ouazzani; A. Sefiani


Book ID
116508668
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
152 KB
Volume
499
Category
Article
ISSN
0378-1119

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Variants of NOD1 and NOD2 genes display
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Background: NOD2 is involved in Crohn's disease (CD), but the role of NOD1 remains unclear. Anti-Saccharomyces cerevisiae antibodies (ASCA) are higher in CD patients and some of their relatives. Using family-based analyses we investigated the relationships between NOD2 mutations, NOD1 ΓΎ32656 variant