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GeneScanning analysis of Ig/TCR gene rearrangements to detect clonality in canine lymphomas

✍ Scribed by Fabio Gentilini; Claudia Calzolari; Maria E. Turba; Giuliano Bettini; Paolo Famigli-Bergamini

Book ID
116966119
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
698 KB
Volume
127
Category
Article
ISSN
0165-2427

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## Detection of clonal T-cell receptor (TCR )-chain gene rearrangement is a promising approach to distinguish between cutaneous T-cell lymphomas (CTCLs) and reactive T-cell infiltrates. Despite the improved sensitivity by using the polymerase chain reaction (PCR) rather than Southern blot analysis