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GeneScan analysis to detect clonality of T-cell receptor γ gene rearrangement in feline lymphoid neoplasms

✍ Scribed by Hiroyuki Mochizuki; Kenji Nakamura; Hirofumi Sato; Yuko Goto-Koshino; Masahiko Sato; Masashi Takahashi; Kenjiro Fukushima; Ko Nakashima; Yasuhito Fujino; Koichi Ohno; Kazuyuki Uchida; Hiroyuki Nakayama; Hajime Tsujimoto


Book ID
116967075
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
573 KB
Volume
145
Category
Article
ISSN
0165-2427

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## Detection of clonal T-cell receptor (TCR )-chain gene rearrangement is a promising approach to distinguish between cutaneous T-cell lymphomas (CTCLs) and reactive T-cell infiltrates. Despite the improved sensitivity by using the polymerase chain reaction (PCR) rather than Southern blot analysis