## Abstract Chronic inflammation is an established risk factor for colorectal cancer (CRC), and polymorphisms in genes regulating inflammatory processes appear to alter the risk for neoplasia and the efficacy of nonsteroidal antiβinflammatory drugs in CRC chemoprevention. We examined the associatio
Genes involved with folate uptake and distribution and their association with colorectal cancer risk
β Scribed by Jane C. Figueiredo; A. Joan Levine; Won H. Lee; David V. Conti; Jenny N. Poynter; Peter T. Campbell; David Duggan; Juan Pablo Lewinger; Maria Elena Martinez; Cornelia M. Ulrich; Polly Newcomb; John Potter; Paul J. Limburg; John Hopper; Mark A. Jenkins; Loic Le Marchand; John A. Baron; Robert W. Haile
- Book ID
- 106383005
- Publisher
- Springer Netherlands
- Year
- 2009
- Tongue
- English
- Weight
- 231 KB
- Volume
- 21
- Category
- Article
- ISSN
- 0957-5243
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
There is evidence supporting a multistep genetic model for colorectal tumorigenesis. In familial adenomatosis polyposis (FAP), the inherited defect is a mutation in the APC gene. The vast majority of all sporadic colorectal cancers also show mutations in the APC gene, and the tumorigenesis in sporad