๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Genes as drugs: the social shaping of gene therapy and the reconstruction of genetic disease

โœ Scribed by Paul A. Martin


Book ID
108541010
Publisher
John Wiley and Sons
Year
1999
Tongue
English
Weight
97 KB
Volume
21
Category
Article
ISSN
0141-9889

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The bacterial enzyme cytosine deaminase (CD) catalyzes the conversion of 5-fluorocytosine (5-FC) to the lethal 5-fluorouracil (5-Fu) and so provides a useful system for selective killing of gene-modified mammalian tumor cells. Cloning of the CD gene from Escherichiu coli and expression in human tumo