✦ LIBER ✦

Transfer and expression of the human multiple drug resistance gene as potential human gene therapy

✍ Scribed by Arthur Bank; Maureen Ward; Christine Richardson; Patricia Pioli; Charles Hesdorffer

Publisher: Springer
Year: 1995
Tongue: English
Weight: 724 KB
Volume: 18
Category: Article
ISSN: 0920-9069
DOI: 10.1007/bf00744327

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Localization of the human multiple drug

Localization of the human multiple drug resistance gene,MDR1, to 7q21.1

✍ D. F. Callen; E. Baker; R. N. Simmers; R. Seshadri; I. B. Roninson 📂 Article 📅 1987 🏛 Springer 🌐 English ⚖ 321 KB

Multiple drug resistance has been shown to be associated with amplification/increased expression of a gene designated MDR. The localization of one member of the MDR gene family, MDR1, to the long arm of chromosome 7 by in situ hybridization is reported.

Retro viral mediated efficient transfer

Retro viral mediated efficient transfer andexpression of multiple drug resistance gene to human leukemic cells

✍ Jian-xin Fu; Wei Wang; Jian-nong Cen; Jian-yong Li; Chang-geng Ruan; Zi-xing Che 📂 Article 📅 2000 🏛 Chinese Anti-Cancer Association 🌐 English ⚖ 521 KB

Liposome-mediated functional expression

Liposome-mediated functional expression of multiple drug resistance gene in human bone marrow CD34+cells

✍ Cao Wenjing; Zou Ping 📂 Article 📅 2004 🏛 Springer-Verlag 🌐 Chinese ⚖ 213 KB

Multiple drug resistance gene expression

Multiple drug resistance gene expression in human renal cell cancer is associated with the histologic subtype

✍ Christoph F. Rochlitz; Hartmut Lobeck; Stefan Peter; Jürgen Reuter; Benno Mohr; 📂 Article 📅 1992 🏛 John Wiley and Sons 🌐 English ⚖ 623 KB

Overexpression of p170 glycoprotein, the product of the multiple drug resistance (mdr) gene, has been associated with resistance to various cytotoxic drugs used in the treatment of human neoplasms. Normal renal epithelial cells express p170 as a function of their secretory capacity. Because renal ce

Assessment of Herpesvirus saimiri as a p

Assessment of Herpesvirus saimiri as a potential human gene therapy vector

✍ Stevenson, Alex J.; Cooper, Matthew; Griffiths, Joanne C.; Gibson, Paul C.; Whit 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 463 KB

Herpesvirus saimiri has characteristics that make it amenable to development as a gene therapy vector. The viral genome is thought to be capable of accommodating large quantities of heterologous DNA while the virus itself can infect many different cell types. Virus infection has been shown in many c

Utility of the polymerase chain reaction

Utility of the polymerase chain reaction in detection of gene expression in drug-resistant human tumors

✍ Kevin J. Scanlon; Mohammed Kashani-Sabet 📂 Article 📅 1989 🏛 John Wiley and Sons 🌐 English ⚖ 659 KB

Recently, an enzymatic amplification method, the polymerase chain reaction (PCR), was modified to amplify a sequence of a drug resistance gene. The PCR assay can confirm data achieved by conventional molecular biology techniques, while requiring less time and fewer patient cells. It can be quantitat