✦ LIBER ✦

Generation of pyrrolo[2,3-d]pyrimidines. Unexpected products in the multicomponent reaction of 6-aminopyrimidines, dimedone, and arylglyoxal

✍ Scribed by Jairo Quiroga; Paola A. Acosta; Silvia Cruz; Rodrigo Abonía; Braulio Insuasty; Manuel Nogueras; Justo Cobo

Publisher: Elsevier Science
Year: 2010
Tongue: French
Weight: 857 KB
Volume: 51
Category: Article
ISSN: 0040-4039
DOI: 10.1016/j.tetlet.2010.08.021

No coin nor oath required. For personal study only.

✦ Synopsis

A series of 6-aryl-5-(1-cyclohexen-1-yl)pyrrolo[2,3-d]pyrimidines 9a-q were obtained by the three-component reaction between 6-aminopyrimidines 6, 7, 8, dimedone 2, and arylglyoxal 5a,b. The unexpected cyclization process was established by NMR and X-ray diffraction measurements.

📜 SIMILAR VOLUMES

ChemInform Abstract: Generation of Pyrro

ChemInform Abstract: Generation of Pyrrolo[2,3-d]pyrimidines. Unexpected Products in the Multicomponent Reaction of 6-Aminopyrimidines, Dimedone, and Arylglyoxal.

✍ Jairo Quiroga; Paola A. Acosta; Silvia Cruz; Rodrigo Abonia; Braulio Insuasty; M 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 30 KB 👁 1 views

Pyrrolopyrimidines. 4. A convenient meth

Pyrrolopyrimidines. 4. A convenient method for the production of 6-(2-aminovinyl)-5-nitropyrimidines and their transformation into pyrrolo[3,2-d]pyrimidines

✍ Yu. N. Tkachenko; E. B. Tsupak; A. F. Pozharskii 📂 Article 📅 2000 🏛 Springer US 🌐 English ⚖ 231 KB

ChemInform Abstract: Reductive Cyclizati

ChemInform Abstract: Reductive Cyclization of 6-Cyanomethyl-5-nitropyrimidines - An Efficient Route to 7-Alkyl-5H-pyrrolo(3,2-d)pyrimidines and 6-Amino-7, 7-dialkyl-7H-pyrrolo(3,2-d)pyrimidines. Utilization in the Synthesis of 9-Deaza Analogues of DHPA.

✍ M. OTMAR; M. MASOJIDKOVA; A. HOLY 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 33 KB 👁 1 views

Reactions of uracils, 16: Substituted 6-

Reactions of uracils, 16: Substituted 6- vinyl-2,4(1H,3H)-pyrimidinediones in cycloaddition and Michael-type reactions: Pyrido[2,3-d]pyrimidines, pyrrolo[3,4-c]pyridines, and quinazolines

✍ Walsh, Eileen B. ;Wamhoff, Heinrich 📂 Article 📅 1989 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 686 KB

ChemInform Abstract: Pyrrolopyrimidines.

ChemInform Abstract: Pyrrolopyrimidines. Part 4. A Convenient Method for the Production of 6-(2-Aminovinyl)-5-nitropyrimidines and Their Transformation into Pyrrolo[3,2-d]pyrimidines.

✍ Yu. N. Tkachenko; E. B. Tsupak; A. F. Pozharskii 📂 Article 📅 2000 🏛 John Wiley and Sons ⚖ 29 KB 👁 2 views

Generation of 6,7-Dihydro-5H-1,3,4-thiad

Generation of 6,7-Dihydro-5H-1,3,4-thiadiazolo[3,2-a]pyridines — Unexpected Products in the Reaction of 5-Ethylthio-1,3,4-thiadiazole-2-amine and 3-(Dimethylamino)propiophenones

✍ Jairo Quiroga; Braulio Insuasty; Pedro Hernandez; Rodolfo Moreno; Regina H. de A 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 447 KB 👁 2 views

pyridines 4a-e was prepared by the reaction of 5-ethylthio-1,3,4-thiadiazole-2-amine (1) and p-substituted 3-(dimeth-1,3,4-Thiadiazoles find a variety of applications as antibiotic, antiinflammatory or bacteriostatic agents and as pesticides [1] [2] . These biological activities have stimulated us t