Induced pluripotent stem cells generated
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Reto Eggenschwiler; Tobias Cantz
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Article
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2009
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John Wiley and Sons
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English
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๐ 1 views
Pluripotent stem cells have been generated from mouse and human somatic cells by viral expression of the transcription factors Oct4, Sox2, Klf4, and c-Myc. A major limitation of this technology is the use of potentially harmful genome-integrating viruses. Here, we generate mouse induced pluripotent