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Generation of mammaglobin-A-specific CD4 T cells and identification of candidate CD4 epitopes for breast cancer vaccine strategies

โœ Scribed by Carsten T. Viehl; Daniel M. Frey; Chanpheng Phommaly; Tingting Chen; Timothy P. Fleming; William E. Gillanders; Timothy J. Eberlein; Peter S. Goedegebuure


Publisher
Springer US
Year
2007
Tongue
English
Weight
364 KB
Volume
109
Category
Article
ISSN
0167-6806

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## Abstract Mammaglobinโ€A is highly overexpressed in breast cancer cell lines and primary breast tumors. This pattern of expression is restricted to mammary epithelium and metastatic breast tumors. Thus, mammaglobinโ€Aโ€specific T cell immune responses may provide an important approach for the design