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Generation of free radicals by simple prenylated hydroquinone derivatives, natural antitumor agents from the marine urochordate Aplidium californicum

โœ Scribed by Cotelle, N.; Moreau, S.; Cotelle, P.; Catteau, J. P.; Bernier, J. L.; Henichart, J. P.

Book ID
126088031
Publisher
American Chemical Society
Year
1991
Tongue
English
Weight
728 KB
Volume
4
Category
Article
ISSN
0893-228X

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Simple prenylated hydroquinone derivativ
Simple prenylated hydroquinone derivatives from the marine urochordate aplidium californicum. Natural anticancer and antimutagenic agents.
โœ Bruce M. Howard; Kathleen Clarkson; R.L. Bernstein ๐Ÿ“‚ Article ๐Ÿ“… 1979 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 229 KB

The structures and syntheses of prenylhydroquinone (I-), 6-hydroxy-2,2\_dimethylchromene (21, and prenylquinone (3), which are natural products isolaied from the-marine col%ial tunicate Aplidium californicum, are described. Prenylhydroquinone shows in vivo activity against P388 lymphocytic leukemia