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Generation of a Human Anti-Tumor Necrosis Factor-α Monoclonal Antibody by in Vitro Immunization with a Multiple Antigen Peptide

✍ Scribed by FUJIKI, Tsukasa; TSUJI, Atsuji; MATSUMOTO, Shin-ei; YAMASHITA, Makiko; TERUYA, Kiichiro; SHIRAHATA, Sanetaka; KATAKURA, Yoshinori


Book ID
126714046
Publisher
Japan Science and Technology Information Aggregator, Electronic
Year
2010
Tongue
English
Weight
205 KB
Volume
74
Category
Article
ISSN
0916-8451

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By in situ FTIR ATR measurements, the antibody (AB) recognition of human tumor necrosis factor-a (TNFa) immobilized on the Ge surface of a multiple internal reflection element (MIRE) was investigated. The experiments were performed in aqueous environment in a flow-through cell. After immobilization