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Decrease in cellularity and expression of adhesion molecules by anti–tumor necrosis factor α monoclonal antibody treatment in patients with rheumatoid arthritis

✍ Scribed by Paul P. Tak; Peter C. Taylor; Ferdinand C. Breedveld; Tom J. M. Smeets; Mohamed R. Daha; Philip M. Kluin; A. Edo Meinders; Ravinder N. Maini

Publisher: John Wiley and Sons
Year: 1996
Tongue: English
Weight: 882 KB
Volume: 39
Category: Article
ISSN: 0004-3591
DOI: 10.1002/art.1780390702

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## Abstract ## Objective Cardiovascular disease is the major cause of excessive mortality in rheumatoid arthritis (RA). Atherosclerosis and RA share similar inflammatory mechanisms that include involvement of tumor necrosis factor α (TNFα). Anti‐TNFα antibody improved endothelial function in RA pa