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Generation and functional assessment of antigen-specific T cells stimulated by fusions of dendritic cells and allogeneic breast cancer cells

✍ Scribed by Shigeo Koido; Yasuhiro Tanaka; Hisao Tajiri; Jianlin Gong


Book ID
116959502
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
557 KB
Volume
25
Category
Article
ISSN
0264-410X

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Dendritic cells (DCs) are "professional" antigen-presenting cells capable of stimulating T-cell proliferation and cytotoxicity when loaded with and presenting specific antigens, including tumor antigens. We demonstrated the stimulation of an autologous cytotoxic T-cell response elicited by DC loaded