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Generation and functional analysis of monoclonal antibodies against the second extracellular loop of human M3 muscarinic acetylcholine receptor

✍ Scribed by Hiroto Tsuboi; Yumi Nakamura; Mana Iizuka; Naomi Matsuo; Isao Matsumoto; Takayuki Sumida


Book ID
113057894
Publisher
Springer
Year
2011
Tongue
English
Weight
432 KB
Volume
22
Category
Article
ISSN
1439-7595

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The effects of anti-peptide antibodies against the second extracellular loop of human M2 muscarinic receptor on transmembrane potentials and currents in guinea pig single ventricular cells were analyzed using whole-cell patch clamp technique. These effects were compared with those of the muscarinic