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Generation and Characterization of two Monoclonal Self-Associating IgG Rheumatoid Factors from a Rheumatoid Synovium

✍ Scribed by Edward W. Lu; Michael Deftos; Helen Tighe; Dennis A. Carson; Pojen P. Chen


Publisher
John Wiley and Sons
Year
1992
Tongue
English
Weight
411 KB
Volume
35
Category
Article
ISSN
0004-3591

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Generation and molecular analyses of two
✍ Edward W. Lu; Michael Deftos; Tsaiwei Olee; De-Feng Huang; Rafael W. Soto-Gil; D πŸ“‚ Article πŸ“… 1993 πŸ› John Wiley and Sons 🌐 English βš– 971 KB

To study the Ig genes that encode IgG rheumatoid factor (IgG-RF) from rheumatoid synovial fluid. Methods. We used rheumatoid synovial fluid B cells to generate IgG-RF-secreting hybridomas. We then characterized their binding properties and determined their nucleotide sequences. Results. Two monosp