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Generation and characterization of a constitutively active Stat3 protein

✍ Scribed by Juan A. Barboza; Shuguang Wang; Timothy S. Schaefer

Book ID
111600886
Publisher
Springer
Year
2004
Tongue
English
Weight
222 KB
Volume
31
Category
Article
ISSN
0301-4851

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Curcumin suppresses constitutive activat
Curcumin suppresses constitutive activation of STAT-3 by up-regulating protein inhibitor of activated STAT-3 (PIAS-3) in ovarian and endometrial cancer cells
✍ Manush Saydmohammed; Doina Joseph; Viqar Syed πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons 🌐 English βš– 332 KB

## Abstract Signal transducer and activator of transcription‐3 (STAT‐3) is constitutively activated in ovarian and endometrial cancers and is implicated in uncontrolled cell growth. Thus, its disruption could be an effective approach to control tumorigenesis. Curcumin is a dihydroxyphenolic compoun