✦ LIBER ✦

Inhibition of constitutively active Stat3 suppresses proliferation and induces apoptosis in glioblastoma multiforme cells

✍ Scribed by Rahaman, Shaik Ohidar; Harbor, Phyllis C; Chernova, Olga; Barnett, Gene H; Vogelbaum, Michael A; Haque, S Jaharul

Book ID: 110067178
Publisher: Nature Publishing Group
Year: 2002
Tongue: English
Weight: 609 KB
Volume: 21
Category: Article
ISSN: 0950-9232
DOI: 10.1038/sj.onc.1206047

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Inhibition of constitutively active Stat

Inhibition of constitutively active Stat3 suppresses growth of human ovarian and breast cancer cells

✍ Burke, William M; Jin, Xiaohong; Lin, Huey-Jen; Huang, Melinda; Liu, Rebecca; Re 📂 Article 📅 2001 🏛 Nature Publishing Group 🌐 English ⚖ 313 KB

Inhibition of ALK enzymatic activity in

Inhibition of ALK enzymatic activity in T-cell lymphoma cells induces apoptosis and suppresses proliferation and STAT3 phosphorylation independently of Jak3

✍ Marzec, Michal; Kasprzycka, Monika; Ptasznik, Andrzej; Wlodarski, Pawel; Zhang, 📂 Article 📅 2005 🏛 Nature Publishing Group 🌐 English ⚖ 401 KB

Histone deacetylase inhibitor, FK228, in

Histone deacetylase inhibitor, FK228, induces apoptosis and suppresses cell proliferation of human glioblastoma cells in vitro and in vivo

✍ Hiroki Sawa; Hiromi Murakami; Masaoki Kumagai; Matsuyoshi Nakasato; Shigeru Yama 📂 Article 📅 2004 🏛 Springer-Verlag 🌐 English ⚖ 508 KB

Inhibition of STAT3 activity with STAT3

Inhibition of STAT3 activity with STAT3 antisense oligonucleotide (STAT3-ASO) enhances radiation-induced apoptosis in DU145 prostate cancer cells

✍ D.P Calvin; S Nam; R Buettner; M Sekharam; J Torres-Roca; R Jove 📂 Article 📅 2003 🏛 Elsevier Science 🌐 English ⚖ 21 KB

A small molecule, LLL12 inhibits constit

A small molecule, LLL12 inhibits constitutive STAT3 and IL-6-induced STAT3 signaling and exhibits potent growth suppressive activity in human multiple myeloma cells

✍ Li Lin; Don M. Benson Jr.; Stephanie DeAngelis; Courtney E. Bakan; Pui-Kai Li; C 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 French ⚖ 891 KB

## Abstract We characterized the effects of a newly developed signal transducers and activators of transcription 3 (STAT3) inhibitor, LLL12 in multiple myeloma (MM) cells. LLL12 specifically inhibited STAT3 phosphorylation, nuclear localization, DNA binding activity, down‐regulated STAT3 downstream

Curcumin suppresses constitutive activat

Curcumin suppresses constitutive activation of STAT-3 by up-regulating protein inhibitor of activated STAT-3 (PIAS-3) in ovarian and endometrial cancer cells

✍ Manush Saydmohammed; Doina Joseph; Viqar Syed 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 332 KB

## Abstract Signal transducer and activator of transcription‐3 (STAT‐3) is constitutively activated in ovarian and endometrial cancers and is implicated in uncontrolled cell growth. Thus, its disruption could be an effective approach to control tumorigenesis. Curcumin is a dihydroxyphenolic compoun