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Generating a High Affinity Scorpion Toxin Receptor in KcsA-Kv1.3 Chimeric Potassium Channels

โœ Scribed by Legros, C.


Book ID
118162333
Publisher
The American Society for Biochemistry and Molecular Biology
Year
2000
Tongue
English
Weight
284 KB
Volume
275
Category
Article
ISSN
0021-9258

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Solution structure of maurotoxin, a scor
โœ E. Blanc; J.M. Sabatier; R. Kharrat; S. Meunier; M. El Ayeb; J. Van Rietschoten; ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 488 KB ๐Ÿ‘ 2 views

Maurotoxin (MTX), purified from the scorpionid Scorpio maurus is a potent ligand for potassium channels. It shows a broad specificity as being active on Kv1.1 (Kd โ€ซุโ€ฌ 37 nM), Kv1.2 (Kd โ€ซุโ€ฌ 0.8 nM), Kv1.3 (Kd โ€ซุโ€ฌ 150 nM) voltage-gated potassium channels, as well as on small-conductance calcium-activa