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General Strategies toward the Syntheses of Macrolide Antibiotics. The Total Syntheses of 6-Deoxyerythronolide B and Oleandolide

✍ Scribed by Evans, David A.; Kim, Annette S.; Metternich, Rainer; Novack, Vance J.


Book ID
118040952
Publisher
American Chemical Society
Year
1998
Tongue
English
Weight
931 KB
Volume
120
Category
Article
ISSN
0002-7863

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## Abstract The latrunculins are highly selective actin‐binding marine natural products and as such play an important role as probe molecules for chemical biology. A short, concise and largely catalysis‐based approach to this family of bioactive macrolides is presented. Specifically, the macrocycli