General method for the synthesis of cycl
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Michael A Walker; Timothy Johnson
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Article
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2001
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Elsevier Science
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French
โ 82 KB
A number of cyclic peptides, wherein the i and i+1 residue side chains are joined by an alkyl linker and a Weinreb amide is present at the C-terminus, were synthesized. Using LiCl to solubilize these peptides in THF the C-terminus can be readily converted to an activated carbonyl such as an aldehyde