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General method for assessing bioavailability of drugs undergoing reversible metabolism in a linear system

โœ Scribed by S. S. Hwang; W. F. Bayne

Publisher
John Wiley and Sons
Year
1986
Tongue
English
Weight
196 KB
Volume
75
Category
Article
ISSN
0022-3549

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โœ Haiyung Cheng; Linyee Shum ๐Ÿ“‚ Article ๐Ÿ“… 1993 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 412 KB ๐Ÿ‘ 2 views

A method has been derived for calculating the mean absorption time of an oral drug and its interconversion metabolite which is generated from the drug systemically and presystemically. The method evolves from the convolution integral and requires plasma AUC and AUMC values after separate intravenous