A method has been derived for calculating the mean absorption time of an oral drug and its interconversion metabolite which is generated from the drug systemically and presystemically. The method evolves from the convolution integral and requires plasma AUC and AUMC values after separate intravenous
Deconvolution method for assessing the absorption of a drug with reversible metabolic pathways
β Scribed by Stephen Hwang; Mark Knowles
- Publisher
- John Wiley and Sons
- Year
- 1994
- Tongue
- English
- Weight
- 363 KB
- Volume
- 83
- Category
- Article
- ISSN
- 0022-3549
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