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General approach to chiroptical characterization of binding of prochiral and chiral 1,4-benzodiazepin-2-ones to human serum albumin

✍ Scribed by Andrzej Konował; Günther Snatzke; Tanja Alebić-Kolbah; Franjo Kajfez̆; Slobodan Rendić; Vitomir S̆unjić


Book ID
115774833
Publisher
Elsevier Science
Year
1979
Tongue
English
Weight
612 KB
Volume
28
Category
Article
ISSN
0006-2952

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Correlation between binding parameters of 6 benzodiazepines to free human serum albumin (HSA) and chromatographic retention parameters on the HSA stationary phase (HSA-SP) was better than the similar correlation with alpha-1-acid glycoprotein (AGP). Still better correlation was obtained between bind