𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Gene–environment interactions for complex traits: definitions, methodological requirements and challenges

✍ Scribed by Dempfle, Astrid; Scherag, André; Hein, Rebecca; Beckmann, Lars; Chang-Claude, Jenny; Schäfer, Helmut


Book ID
109847728
Publisher
Nature Publishing Group
Year
2008
Tongue
English
Weight
134 KB
Volume
16
Category
Article
ISSN
1018-4813

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Gene-environment interaction tests for d
✍ Thomas J. Hoffmann; Christoph Lange; Stijn Vansteelandt; Nan M. Laird 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 156 KB

## Abstract When testing for genetic effects, failure to account for a gene‐environment interaction can mask the true association effects of a genetic marker with disease. Family‐based association tests are popular because they are completely robust to population substructure and model misspecifica

Sample size requirements for indirect as
✍ Rebecca Hein; Lars Beckmann; Jenny Chang-Claude 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 329 KB 👁 2 views

## Abstract Association studies accounting for gene–environment interactions (G × E) may be useful for detecting genetic effects. Although current technology enables very dense marker spacing in genetic association studies, the true disease variants may not be genotyped. Thus, causal genes are sear