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Gene trap in hepatocellular carcinoma (HCC) by hepatitis B virus (HBV) DNA insertional mutagenesis analysis

โœ Scribed by D. Gozuacik; Y. Murakami; K. Saigo; M. Chami; T. Okanoue; T. Urashima; T. Kenmochi; T. Ochiai; C. Brechot; P. Paterlini-Brechot


Book ID
119527185
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
157 KB
Volume
34
Category
Article
ISSN
0168-8278

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We have previously reported an analysis of DNA extracted from 31 primary liver tumors where, in 25 cases, we found chromosomal integration of hepatitis B virus DNA sequences. We describe here an investigation of the extent of the viral genome at each integration site in 15 of the hepatitis B virus D