Hepatitis B virus (HBV) DNA in hepatocellular carcinoma (HCC) and/or cirrhotic livers of Japanese patients in Japan was investigated by molecular hybridization utilizing a 32P-labeled cloned HBV DNA of adr subtype. Among 24 HCC cases, 9 (37.5%) were positive for serum HBsAg and 10 (41.7%), including
Detection of hepatitis B virus dna in hepatocellular carcinoma: Analysis by hybridization with subgenomic dna fragments
โ Scribed by Jen-Yang Chen; Tim J. Harrison; Chue-Shue Lee; Ding-Shinn Chen; Arie J. Zuckerman
- Publisher
- John Wiley and Sons
- Year
- 1988
- Tongue
- English
- Weight
- 619 KB
- Volume
- 8
- Category
- Article
- ISSN
- 0270-9139
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โฆ Synopsis
We have previously reported an analysis of DNA extracted from 31 primary liver tumors where, in 25 cases, we found chromosomal integration of hepatitis B virus DNA sequences. We describe here an investigation of the extent of the viral genome at each integration site in 15 of the hepatitis B virus DNA-positive tumors using
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