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Gene transfer into hepatocytes mediated by herpes simplex virus–Epstein-Barr virus hybrid amplicons

✍ Scribed by Lars Müller; Okay Saydam; Yoshinaga Saeki; Irma Heid; Cornel Fraefel

Book ID
113766911
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
370 KB
Volume
123
Category
Article
ISSN
0166-0934

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Hybrid herpes simplex virus/Epstein–Barr
Hybrid herpes simplex virus/Epstein–Barr virus amplicon viral vectors confer enhanced transgene expression in primary human tumors and human bone marrow-derived mesenchymal stem cells
✍ Kian Chuan Sia; Wei Kin Chong; Ivy A. W. Ho; Yulyana Yulyana; Berwini Endaya; Hu 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 452 KB

Background Herpes simplex virus type-1 (HSV-1) amplicon vectors are attractive tools for gene transfer because of their large DNA insert capacity, their broad host range of vector transduction and a minimal immune response as a result of the absence of helper viruses during viral packaging. However,