๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Gene therapy techniques

โœ Scribed by Fred Levine; Theodore Friedmann


Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
583 KB
Volume
2
Category
Article
ISSN
0958-1669

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โœฆ Synopsis


The most dramatic event of the past year in the field of gene therapy has been the initiation of clinical trials involving the introduction of genetically altered cells into human beings. Four studies, three involving new approaches to cancer therapy and one involving the treatment of adenosine deaminase deficiency, are presently under way. There has also been significant recent progress in the technology of gene transfer relevant to gene therapy. This progress, along with the recent clinical therapy trials, is the subject of this review.


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furthermore found that cell divisions of purified CD34+CD45RAi\*CD71 ~ cells in vitro is associated with a predictable decrease (37 base pairs per division) in mean telomere length in the cultured progeny of the cells. Taken together, these observations strongly suggest that the proliferative potent