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Gene Therapy of X-Linked Severe Combined Immunodeficiency

✍ Scribed by Salima Hacein-Bey-Abina; Alain Fischer; Marina Cavazzana-Calvoa


Publisher
Carden Jennings Publishing
Year
2002
Tongue
English
Weight
75 KB
Volume
76
Category
Article
ISSN
0925-5710

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Gene therapy of severe combined immunode
✍ Marina Cavazzana-Calvo; Salima Hacein-Bey; Frank Yates; J. P. de Villartay; F. L πŸ“‚ Article πŸ“… 2001 πŸ› John Wiley and Sons 🌐 English βš– 88 KB πŸ‘ 2 views
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✍ Robertson Parkman; Erwin W Gelfand πŸ“‚ Article πŸ“… 1991 πŸ› Elsevier Science 🌐 English βš– 741 KB

Patients with severe combined immunodeficiency disease represent a model for the first clinical applications of gene therapy. Present attempts use insertion of the human adenosine deaminase gene into the peripheral blood T lymphocytes of patients who lack this gene. The ultimate treatment, however,