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Mutations in the gene for the common gamma chain (γc) in X-linked severe combined immunodeficiency

✍ Scribed by Sebastian D. Fugmann; Susanna Müller; Wilhelm Friedrich; Claus R. Bartram; K. Schwarz

Publisher
Springer
Year
1998
Tongue
English
Weight
23 KB
Volume
103
Category
Article
ISSN
0340-6717

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Mutations in the common gamma chain (y~ or IL2RG) of the interleukin-2, -4, -7, -9 and -15 receptors have been found to cause X-linked severe combined immunodeficiency (SCIDX1). We report here on the mutations identified in a further ten families. Two of the mutations identified have occurred twice