𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Gene therapy of cancer through restoration of tumor-suppressor functions?

✍ Scribed by Theodore Friedmann

Book ID
102673103
Publisher
John Wiley and Sons
Year
1992
Tongue
English
Weight
881 KB
Volume
70
Category
Article
ISSN
0008-543X

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Galectin-4 functions as a tumor suppress
Galectin-4 functions as a tumor suppressor of human colorectal cancer
✍ Arun Satelli; Prema S. Rao; Seshadri Thirumala; U. Subrahmanyeswara Rao πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons 🌐 French βš– 796 KB

## Abstract Development of colorectal cancer (CRC) involves a series of genetic alterations with altered expression of proteins and cell signaling pathways. Here, we identified that galectin‐4 (gal‐4), a marker of differentiation, was down‐regulated in CRC. The goal of this work was to determine th

Restoration of wild-type p53 function in
Restoration of wild-type p53 function in human cancer: Relevance for tumor therapy
✍ Gianluca Bossi; Ada Sacchi πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 English βš– 480 KB

## Abstract ## Background. In the majority of human cancers, the tumor suppressor activity of p53 is impaired because of mutational events or interactions with other proteins (ie, MDM2). The loss of p53 function is responsible for increased aggressiveness of cancers, while tumor chemoresistance an