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Gene therapy for osteoporosis: evaluation in a murine ovariectomy model

โœ Scribed by Baltzer, AWA; Whalen, JD; Wooley, P; Latterman, C; Truchan, LM; Robbins, PD; Evans, CH

Book ID
110039038
Publisher
Nature Publishing Group
Year
2001
Tongue
English
Weight
649 KB
Volume
8
Category
Article
ISSN
0969-7128

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## Abstract Female SJL/J mice, suffering from experimental autoimmune encephalomyelitis (EAE), were injected with 1 ร— 10^7^ cells from a syngeneic fibroblast line transduced with a retroviral vector designed to encode proteolipid protein (101โ€157) targeted for secretion. A striking abrogation of bo