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Gene targeting in mouse embryos mediated by RecA and modified single-stranded oligonucleotides

✍ Scribed by Jee Hyun Kang; Kwang Sung Ahn; Soon Young Heo; Ji Young Won; Hosup Shim


Book ID
107427040
Publisher
Society for In Vitro Biology
Year
2008
Tongue
English
Weight
193 KB
Volume
44
Category
Article
ISSN
1475-2689

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## Abstract We report here a novel approach to direct gene expression in the mouse somite based on the combined application of adenovirus‐mediated gene delivery and whole embryo ex vivo culture. As proof of principle, we show functional analysis of somites microinjected with an engineered virus exp