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Gene targeting in embryonic stem cells: the new physiology and metabolism

✍ Scribed by R. W. Moreadith; Nina Butwell Radford

Book ID
105797286
Publisher
Springer
Year
1997
Tongue
English
Weight
449 KB
Volume
75
Category
Article
ISSN
0946-2716

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## Abstract Mouse embryonic stem cell lines offer an attractive route for introducing rare genetic alternations into the gene pool since the cells can be pre‐screened in culture and the mutations then transmitted into the germline through chimera production. Two applications of this technique seem