Three mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene were discovered in a pancreas-insufficient patient with cystic fibrosis (CF) who displayed an uncommon combination of almost normal chloride concentration in sweat tests and typical symptoms of gastrointestinal an
Disruption of the cystic fibrosis transmembrane conductance regulator gene in embryonic stem cells by gene targeting
β Scribed by Rosemary Ratcliff; Martin J. Evans; Joanne Doran; Brandon J. Wainwaright; Robert Williamson; William H. Colledge
- Book ID
- 110547240
- Publisher
- Springer Netherlands
- Year
- 1992
- Tongue
- English
- Weight
- 706 KB
- Volume
- 1
- Category
- Article
- ISSN
- 0962-8819
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Cystic fibrosis transmembrane conductance regulator (CFTR) mRNA transcripts isolated from both expressing and "non-expressing" cell types of normal individuals exhibit differential splicing to a variable extent in a region encoding the putative nucleotide binding fold of the CFTR polypeptide. Sequen
Lipoprotein lipase (LPL) catalyzes the hydrolysis of the core triacylglycerols of plasma very low density lipoproteins (VLDL) and chylomicrons . It thus controls a crucial step in the metabolism of triglycerides of exogenous and endogenous origin. Inherited LPL deficiency is clinically expressed as