✦ LIBER ✦

Gene structure of the human receptor tyrosine kinase RON and mutation analysis in lung cancer samples

✍ Scribed by Debora Angeloni; Alla Danilkovitch-Miagkova; Sergey V. Ivanov; Richard Breathnach; Bruce E. Johnson; Edward J. Leonard; Michael I. Lerman

Publisher: John Wiley and Sons
Year: 2000
Tongue: English
Weight: 277 KB
Volume: 29
Category: Article
ISSN: 1045-2257
DOI: 10.1002/1098-2264(2000)9999:9999<::aid-gcc1015>3.0.co;2-n

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

METPRC mutations in the ron receptor res

METPRC mutations in the ron receptor result in upregulation of tyrosine kinase activity and acquisition of oncogenic potential

✍ Tracy A. Williams; Paola Longati; Luisa Pugliese; Philippe Gual; Alberto Bardell 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 218 KB

Ron and Met are structurally related receptor tyrosine kinases that elicit a complex biological response leading to invasive growth. Naturally occurring point mutations activate the Met kinase in papillary renal carcinomas (MET PRC mutations). By site-directed mutagenesis, we generated homologous am

Analysis of the tyrosine hydroxylase and

Analysis of the tyrosine hydroxylase and dopamine D4 receptor genes in a Croatian sample of bipolar I and unipolar patients

✍ Oruč, L.; Verheyen, G.R.; Furač, I.; Jakovljević, M.; Ivezić, S.; Raeymaekers, P 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 133 KB 👁 1 views

We selected 83 patients with bipolar disorder type I or unipolar recurrent major depression and 71 healthy controls for genetic analysis of the tyrosine hydroxylase and the dopamine D4 receptor gene. No significant association was found between bipolar disorder type I and unipolar recurrent major de

Mutation analysis of NTRK2 and NTRK3, en

Mutation analysis of NTRK2 and NTRK3, encoding 2 tyrosine kinase receptors, in sporadic human medullary thyroid carcinoma reveals novel sequence variants

✍ Oliver Gimm; Heather Dziema; Jessica Brown; Aranzazu De La Puente; Cuong Hoang-V 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 French ⚖ 77 KB

Novel mutations in the promoter and codi

Novel mutations in the promoter and coding region of the human 5-HT1A receptor gene and association analysis in schizophrenia

✍ Kawanishi, Yoichi; Harada, Shoji; Tachikawa, Hirokazu; Okubo, Takehito; Shiraish 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 54 KB 👁 2 views

Dysfunction of serotonin systems has been implicated in schizophrenia. In the present study, the human 5-HT 1A receptor gene containing the 5 untranslated region was screened in order to detect genetic variations, through which alteration of protein function or level of expression might contribute t

Mutation analysis of replicative genes e

Mutation analysis of replicative genes encoding the large subunits of DNA polymerase α and replication factors A and C in human sporadic colorectal cancers

✍ Odilia Popanda; Chun Zheng; J. Richard Magdeburg; Jens Büttner; Thomas Flohr; Eg 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 French ⚖ 91 KB 👁 2 views

We examined cDNAs of the catalytic subunit of DNA polymerase ␣ (185 kDa), the 70 kDa subunit of replication protein A (single-stranded DNA-binding protein) and the 140 kDa subunit of replication factor C for mutations. Surgical specimens from 12 patients with sporadic colon cancer and normal mucosae

Two novel mutant alleles of the gene enc

Two novel mutant alleles of the gene encoding neurotrophic tyrosine kinase receptor type 1 (NTRK1) in a patient with congenital insensitivity to pain with anhidrosis: A splice junction mutation in intron 5 and cluster of four mutations in exon 15

✍ Marek Bodzioch; Katarzyna Lapicka; Charalampos Aslanidis; Marek Kacinski; Gerd S 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 34 KB 👁 1 views

Congenital insensitivity to pain with anhidrosis (CIPA), also called hereditary sensory and autonomic neuropathy type IV (HSAN IV), is caused by mutations of the NTRK1 gene coding for the neurotrophic tyrosine kinase receptor type 1. We report the results of the NTRK1 sequence analysis in a CIPA fam