## Abstract The proliferation and differentiation of hematopoietic precursor cells depend on various cytokines. The suppressor of cytokine signaling‐1 (__SOCS1__) down‐regulates Janus kinases/signal transducers and activators of transcription (__JAK/STAT__) pathway activity and inhibits the biologi
✦ LIBER ✦
Gene-specific and global methylation patterns predict outcome in patients with acute myeloid leukemia
✍ Scribed by Deneberg, S; Grövdal, M; Karimi, M; Jansson, M; Nahi, H; Corbacioglu, A; Gaidzik, V; Döhner, K; Paul, C; Ekström, T J
- Book ID
- 109887371
- Publisher
- Nature Publishing Group
- Year
- 2010
- Tongue
- English
- Weight
- 608 KB
- Volume
- 24
- Category
- Article
- ISSN
- 0887-6924
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## Abstract Tandem duplication (TD) of the __MLL__ or __FLT3__ gene in acute myeloid leukemia (AML) has been reported. We examined whether TD of these two genes occurs simultaneously. We analyzed 13 AML and 2 myelodysplastic syndrome patients, including 6 adult patients with trisomy 11 and 9 pediat