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Gene regulatory networks directing myeloid and lymphoid cell fates within the immune system

✍ Scribed by Peter Laslo; Jagan M.R. Pongubala; David W. Lancki; Harinder Singh


Book ID
116885557
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
810 KB
Volume
20
Category
Article
ISSN
1044-5323

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Considerable progress has been achieved in the identification and analysis of regulatory molecules that orchestrate B and T cell fate determination. IL-7 and Notch signaling appear to represent analogous pathways that direct B and T cell fates, respectively. For the B lineage, it is possible to asse