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Gene of the month: E-cadherin (CDH1)

✍ Scribed by Gall, T. M. H.; Frampton, A. E.


Book ID
121868144
Publisher
BMJ Publishing Group
Year
2013
Tongue
English
Weight
827 KB
Volume
66
Category
Article
ISSN
0021-9746

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## Communicated by Albert de la Chapelle Hereditary diffuse gastric cancer (HDGC) is a cancer predisposition syndrome caused by germline mutation of the gene encoding the tumour-suppressor E-cadherin (CDH1). We describe the search for CDH1 mutations in 36 new diffuse gastric cancer families. All 1