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Cloning and characterization of the human invasion suppressor gene E-cadherin (CDH1)

✍ Scribed by Geert Berx; Katrien Staes; Jolanda van Hengel; Francis Molemans; Marion J.G. Bussemakers; Adrie van Bokhoven; Frans van Roy


Book ID
116154123
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
957 KB
Volume
26
Category
Article
ISSN
0888-7543

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## Communicated by Albert de la Chapelle Hereditary diffuse gastric cancer (HDGC) is a cancer predisposition syndrome caused by germline mutation of the gene encoding the tumour-suppressor E-cadherin (CDH1). We describe the search for CDH1 mutations in 36 new diffuse gastric cancer families. All 1