The c-met proto-oncogene encodes the tyrosine kinase receptor for hepatocyte growth factor (HGF), a potent mitogen and motogen for epithelial cells. Because of its profound effects on cell growth and motility, HGF may be important in the development of cancer metastases in hepatocellular carcinoma (
Gene expressions of c-met and hepatocyte growth factor in chronic liver disease and hepatocellular carcinoma
โ Scribed by Osamu Noguchi; Nobuyuki Enomoto; Takaaki Ikeda; Fumie Kobayashi; Fumiaki Marumo; Chifumi Sato
- Book ID
- 118567269
- Publisher
- Elsevier Science
- Year
- 1996
- Tongue
- English
- Weight
- 781 KB
- Volume
- 24
- Category
- Article
- ISSN
- 0168-8278
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mal and malignant epithelial cells and several other cell The c-met proto-oncogene encodes the tyrosine kinase types, including endothelial cells and melanocytes. 4,5 receptor for hepatocyte growth factor (HGF), a potent It has been reported that the expression of c-Met is enmitogen and motogen for
## Background: This study was designed to evaluate the significance of tumor angiogenesis and angiogenic factors such as hepatocyte growth factor (hgf) and c-met in determining the prognoses of 93 patients with endometrial carcinoma. ## Methods: By immunohistochemical staining, this retrospective