## Background: This study was designed to evaluate the significance of tumor angiogenesis and angiogenic factors such as hepatocyte growth factor (hgf) and c-met in determining the prognoses of 93 patients with endometrial carcinoma. ## Methods: By immunohistochemical staining, this retrospective
Tumor angiognesis, hepatocyte growth factor, and c-Met expression in endometrial carcinoma
β Scribed by R. Konno; S. Wagatsuma; T. Igarashi; H. Yamakawa; S. Sato; A. Yajima
- Book ID
- 117667902
- Publisher
- Elsevier Science
- Year
- 1999
- Tongue
- English
- Weight
- 169 KB
- Volume
- 35
- Category
- Article
- ISSN
- 0959-8049
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The c-met proto-oncogene encodes the tyrosine kinase receptor for hepatocyte growth factor (HGF), a potent mitogen and motogen for epithelial cells. Because of its profound effects on cell growth and motility, HGF may be important in the development of cancer metastases in hepatocellular carcinoma (
mal and malignant epithelial cells and several other cell The c-met proto-oncogene encodes the tyrosine kinase types, including endothelial cells and melanocytes. 4,5 receptor for hepatocyte growth factor (HGF), a potent It has been reported that the expression of c-Met is enmitogen and motogen for