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Gene expression variations: potentialities of master regulator polymorphisms in colorectal cancer risk

โœ Scribed by Pardini, B.; Naccarati, A.; Vodicka, P.; Kumar, R.

Book ID
118033261
Publisher
Oxford University Press
Year
2012
Tongue
English
Weight
212 KB
Volume
27
Category
Article
ISSN
0267-8357

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## Abstract Hereditary nonpolyposis colorectal cancer (HNPCC) is characterized by germline mutations in DNA mismatch repair genes; however, variation in disease expression suggests that there are potential modifying factors. Polymorphisms of the __HFE__ gene, which cause the iron overload disorder