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Gene expression profiling of microglia from the demyelinative lesions in osmotic demyelination syndrome rats

✍ Scribed by Yoshihisa Sugimura; Haruyuki Suzuki; Shintaro Iwama; Hiromi Suzuki; Atsushi Kiyota; Makoto Sawada; Yutaka Oiso

Book ID
116777903
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
70 KB
Volume
68
Category
Article
ISSN
0168-0102

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✍ Shintaro Iwama; Yoshihisa Sugimura; Haruyuki Suzuki; Hiromi Suzuki; Takashi Mura πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons 🌐 English βš– 722 KB

Osmotic demyelination syndrome (ODS) is a serious demyelinating disease in the central nervous system usually caused by rapid correction of hyponatremia. In an animal model of ODS, we previously reported microglial accumulation expressing proinflammatory cytokines. Microglia and astrocytes secreting