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Gene expression profiles in the cellular response to a multinuclear platinum complexe

✍ Scribed by L. Gatti; G.L. Beretta; N. Carenini; E. Corna; F. Zunino; P. Perego


Publisher
Springer
Year
2004
Tongue
English
Weight
265 KB
Volume
61
Category
Article
ISSN
1420-682X

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Exposure of mammalian cells to genotoxic agents evokes a complex cellular response. An ordered series of molecular events is necessary to sense DNA damage, transduce the signal, and ultimately delay the cell cycle or trigger apoptosis. Recently, we have shown that BTG2/TIS21 gene expression was indu