Alterations in gene expression profiles and the DNA-damage response in ionizing radiation-exposed TK6 cells
โ Scribed by Gregory S. Akerman; Barry A. Rosenzweig; Olen E. Domon; Chen-An Tsai; Michelle E. Bishop; Lynda J. McGarrity; James T. MacGregor; Frank D. Sistare; James J. Chen; Suzanne M. Morris
- Publisher
- John Wiley and Sons
- Year
- 2005
- Tongue
- English
- Weight
- 181 KB
- Volume
- 45
- Category
- Article
- ISSN
- 0893-6692
- DOI
- 10.1002/em.20091
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
## Abstract Magnetic resonance imaging with high static magnetic fields (SMFs) has become widely used for medical imaging purposes because SMFs cause fewer genotoxic side effects than ionizing radiation (IR). However, the effect of exposure to high SMFs on global transcription is little understood.
Exposure of mammalian cells to genotoxic agents evokes a complex cellular response. An ordered series of molecular events is necessary to sense DNA damage, transduce the signal, and ultimately delay the cell cycle or trigger apoptosis. Recently, we have shown that BTG2/TIS21 gene expression was indu
## Abstract Carcinogenesis is an important chronic toxicity of metals and metalloids, although their mechanisms of action are still unclear. Comparison of gene expression patterns induced by carcinogenic metals, metalloids, and model carcinogens would give an insight into understanding of their car
## Abstract The successful movement of a newly synthesized protein through the endoplasmic reticulum (ER) and associated membranous compartments is dependent on appropriate recognition by complex processing systems. Failure to perceive appropriately processed or modified intermediates in the pathwa