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Gene expression profile linked to p53 status in hepatitis C virus-related hepatocellular carcinoma

✍ Scribed by Toshimasa Okada; Norio Iizuka; Hisafumi Yamada-Okabe; Naohide Mori; Takao Tamesa; Norikazu Takemoto; Akira Tangoku; Kenji Hamada; Hironobu Nakayama; Takanobu Miyamoto; Shunji Uchimura; Yoshihiko Hamamoto; Masaaki Oka


Book ID
117106066
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
385 KB
Volume
555
Category
Article
ISSN
0014-5793

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Abnormalities of the tumor-suppressor p53 gene have been discovered in human hepatocellular carcinoma (HCC). It is unclear, however, whether HCC related to chronic viral hepatitis is associated with p53 gene alterations. In this study, we have examined p53 abnormalities in HCC associated with hepati